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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AAK1
All Species:
12.73
Human Site:
S519
Identified Species:
40
UniProt:
Q2M2I8
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M2I8
NP_055726.3
863
93578
S519
I
A
Q
F
P
V
V
S
Q
G
G
S
Q
Q
Q
Chimpanzee
Pan troglodytes
XP_001138187
865
93810
S520
I
A
Q
F
P
V
V
S
Q
G
G
S
Q
Q
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531855
473
51892
K169
V
A
R
L
H
Q
C
K
T
P
I
I
H
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHJ0
959
103328
S528
T
A
Q
F
P
V
G
S
Q
G
G
A
Q
Q
Q
Rat
Rattus norvegicus
P0C1X8
962
103742
S532
T
A
Q
F
P
V
V
S
Q
G
G
S
Q
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417663
953
102927
Q514
V
S
Q
F
P
V
M
Q
Q
G
A
P
A
Q
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625109
598
65629
Q294
Q
V
S
M
I
A
F
Q
I
L
G
K
E
C
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40494
810
91014
K490
L
S
P
T
I
T
S
K
S
L
S
S
T
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
53.7
N.A.
80.7
79.9
N.A.
N.A.
71.4
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
54.4
N.A.
83.1
82.7
N.A.
N.A.
77.9
N.A.
N.A.
N.A.
N.A.
50
N.A.
N.A.
P-Site Identity:
100
100
N.A.
6.6
N.A.
80
93.3
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
26.6
N.A.
86.6
93.3
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
63
0
0
0
13
0
0
0
0
13
13
13
0
0
% A
% Cys:
0
0
0
0
0
0
13
0
0
0
0
0
0
13
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
13
% E
% Phe:
0
0
0
63
0
0
13
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
13
0
0
63
63
0
0
0
0
% G
% His:
0
0
0
0
13
0
0
0
0
0
0
0
13
0
0
% H
% Ile:
25
0
0
0
25
0
0
0
13
0
13
13
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
25
0
0
0
13
0
13
0
% K
% Leu:
13
0
0
13
0
0
0
0
0
25
0
0
0
0
0
% L
% Met:
0
0
0
13
0
0
13
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
13
0
63
0
0
0
0
13
0
13
0
0
13
% P
% Gln:
13
0
63
0
0
13
0
25
63
0
0
0
50
63
63
% Q
% Arg:
0
0
13
0
0
0
0
0
0
0
0
0
0
13
0
% R
% Ser:
0
25
13
0
0
0
13
50
13
0
13
50
0
0
0
% S
% Thr:
25
0
0
13
0
13
0
0
13
0
0
0
13
0
0
% T
% Val:
25
13
0
0
0
63
38
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _